Squadron 253 was a squad of SEMME agents in It's Walky!.

Spoiler warning!
Plot and/or ending details follow.

253 and another SEMME squadron, 135, were dispatched by Big Boss to pursue David Walkerton after the latter launched a solo assault on Head Alien's island HQ. 253 was reported as missing in action after the fighting finally ceased, and was most likely KIA.

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